Diabetes

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Browsing Diabetes by Author "Mwabutwa, Emmanuel"

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    Clinical qharacteristics, quality of care and outcomes of patients presenting with diabetes ketoacidosis at Kamuzu Central Hospital
    (Kamuzu University of Health Sciences, 2021-11-11) Mwabutwa, Emmanuel
    Type of Research This will be a cross-sectional study. Problem Diabetes Ketoacidosis is a serious and life threatening complication of diabetes. There is need to understand the clinical characteristics, in-hospital management quality and patient outcomes in view of the increasing numbers of patients being diagnosed and admitted with diabetes at Kamuzu Central Hospital. Study Objectives Broad objectives The primary objective of this study is to describe the clinical characteristics, precipitating factors, management and outcomes of patients with diabetes ketoacidosis at Kamuzu Central Hospital. Specific objectives To describe the proportion of patients with of suboptimal insulin therapy (poor insulin compliance /storage/technique of injection) as a precipitant to DKA To establish clinical characteristics of patients presenting with DKA To analyze point of care on patients with DKA determine time to resolution of DKA, quality of care and outcomes of patients with DKA Data Collection, management and analysis Patients will be recruited from adult medical wards at Kamuzu Central Hospital. A standard questionnaire will be used to collect data. Health passports, patient case files will be reviewed to gather information on patients’ comorbidities and drugs. Collected data will be entered into an electronic database and statistical analysis will be performed using STATA 15.1 software. Descriptive statistics will be used to summarize frequencies and proportions. Chi squared testing will be used to compare categorical variables and t-testing will be used for continuous variables. Research Ethics A written informed consent will be sought from all study participants and confidentiality will be ensured by the study team by following good clinical practice guidelines. Research ethics approval will be sought from the College of Medicine’s research and ethics committee. Expected findings and dissemination We expect to highlight the common clinical characteristics, quality of in-hospital management and outcomes of patients admitted with diabetes ketoacidosis at Kamuzu Central Hospital.