Clinical qharacteristics, quality of care and outcomes of patients presenting with diabetes ketoacidosis at Kamuzu Central Hospital
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Date
2021-11-11
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kamuzu University of Health Sciences
Abstract
Type of Research
This will be a cross-sectional study.
Problem
Diabetes Ketoacidosis is a serious and life threatening complication of diabetes. There is need to
understand the clinical characteristics, in-hospital management quality and patient outcomes in view of
the increasing numbers of patients being diagnosed and admitted with diabetes at Kamuzu Central
Hospital.
Study Objectives
Broad objectives
The primary objective of this study is to describe the clinical characteristics, precipitating factors,
management and outcomes of patients with diabetes ketoacidosis at Kamuzu Central Hospital.
Specific objectives
To describe the proportion of patients with of suboptimal insulin therapy (poor insulin compliance
/storage/technique of injection) as a precipitant to DKA
To establish clinical characteristics of patients presenting with DKA
To analyze point of care on patients with DKA determine time to resolution of DKA, quality of care and
outcomes of patients with DKA
Data Collection, management and analysis
Patients will be recruited from adult medical wards at Kamuzu Central Hospital. A standard
questionnaire will be used to collect data. Health passports, patient case files will be reviewed to gather
information on patients’ comorbidities and drugs. Collected data will be entered into an electronic
database and statistical analysis will be performed using STATA 15.1 software. Descriptive statistics will
be used to summarize frequencies and proportions. Chi squared testing will be used to compare
categorical variables and t-testing will be used for continuous variables.
Research Ethics
A written informed consent will be sought from all study participants and confidentiality will be ensured
by the study team by following good clinical practice guidelines. Research ethics approval will be sought
from the College of Medicine’s research and ethics committee. Expected findings and dissemination We expect to highlight the common clinical characteristics, quality of in-hospital management and
outcomes of patients admitted with diabetes ketoacidosis at Kamuzu Central Hospital.
Description
Type of Research
This will be a cross-sectional study.